The Water-AI Nexus Center of Excellence is a first-of-its kind initiative to address water sustainability in AI development while harnessing AI to solve critical water challenges. Founded by the Water Environment Federation (WEF), Amazon, The Water Center at the University of Pennsylvania, and Leading Utilities of the World, the Water-AI Nexus serves as a global hub for knowledge, collaboration, and innovation. It unites leaders in utilities, technology, academia, and finance to accelerate sustainable water management practices while enabling responsible technological advancements.